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Common foods may be the cause, as well as bee or wasp stings, or skin contact with certain fragrances.
Systematic reviews indicate whether or not there exists evidence that drugs differ in their effects in various subgroups of patients, but they do not attempt to set a standard for how results of controlled trials should be applied to patients who would not have been eligible for them.
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Azelastine nasal spray caused birth defects in mouse, rabbit, and rat studies, and olopatadine nasal spray has been associated with adverse effects on fetuses in animal studies.
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At nanomolar concentrations, desloratadine also significantly inhibited expression by HUVECs of P-selectin (), which promotes leukocyte adhesion to endothelial cells and diapedesis.
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