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My brother is 71 and recently he has been diagnosed with Alzheimer's. after hearing a lot of scary stories about useless medications and people losing their relatives because of severe Alzheimer's I am happy that we started right from Galantamine. Immediately after the treatment began my brother started showing signs of improvement. Now he is able to read again, he tells me about what he has read and we discuss this stuff. I can see logic in his thoughts and words and it makes me happy. I would recommend this medication to anyone whose life was damaged by Alzheimer's.
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CMAJ in April found no evidence that drugs, herbal products or vitamin supplements help prevent cognitive decline in healthy older adults.

Pickworth, 2003) and are relatively contraindicated in patients with ischemic heart disease or preexisting cardiac conduction disturbance (increased P-R interval, bundle-branch block, increased QRS).

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Figure 12 is a histogram of the percentage distribution of CIBIC-plus scores attained by patients assigned to each of the two treatment groups who completed 13 weeks of treatment.

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Other general recommendations include management of depression, feelings of guilt, sadness, grief, feelings of worthlessness, anxiety and frustration.

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The use of cholinergic modalities in combination with existing or new therapeutic approaches to target neural, endocrine and immune functions for therapeutic benefit in patients with obesity-related disorders should also be considered.

Recently, biotechnology and pharmaceutical companies have attempted to extend the success of neurotrophin treatment found in animal models of AD to the clinic.

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Overall, 54% galantamine-treated patients and 49% placebo-treated patients reported one or more TEAEs, most of which were mild or moderate in severity.

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An upset stomach is one of the more common complaints of users who supplement with galantamine along with other negative effects such as fatigue, dizziness, loss of appetite, and allergy.

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Extensive testing in clinically typical AD may not be beneficial to patients or families, expending time and energy needed for other purposes.

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Four individuals withdrew from the study because of adverse events.

It is approved for the treatment of mild to moderately severe dementia of Alzheimer type in the USA and for AD with cerebrovascular disease in certain other countries.

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It is a reversible, competitive inhibitor of acetylcholinesterase (AChE), and is the only drug actively marketed for the treatment of AD with proven activity as an allosteric modulator of nicotinic acetylcholine receptors (nAChRs).

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There was an apparent dose dependency with patients taking donepezil doses of 15 mg per day or higher having a two-fold increase in bradycardia (slowed pulse) compared to untreated dementia patients.

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